How Does Vaccination against SARS-CoV-2 Affect Hospitalized Patients with COVID-19?
Autor:
Moreno-Nuñez, Paloma
; Bueno-Cavanillas, Aurora
; San José Saras, Diego
; Vicente-Guijarro, Jorge
; Fernández Chávez, Abelardo
; Aranaz Andrés, Jesús María
Fecha:
07/2022Palabra clave:
Revista / editorial:
Journal of Clinical MedicineCitación:
Moreno-Nunez, P., Bueno-Cavanillas, A., San Jose-Saras, D., Vicente-Guijarro, J., Fernández Chávez, A. C., & Aranaz-Andrés, J. M. (2022). How Does Vaccination against SARS-CoV-2 Affect Hospitalized Patients with COVID-19? Journal of Clinical Medicine, 11(13), 3905. MDPI AG. Retrieved from http://dx.doi.org/10.3390/jcm11133905Tipo de Ítem:
Articulo Revista IndexadaDirección web:
https://www.mdpi.com/2077-0383/11/13/3905Resumen:
Background: The development of effective COVID-19 vaccines has reduced the impact of COVID-19 on the general population. Our study aims to analyze how vaccination modifies the likelihood of death and length of stay in hospitalized patients with COVID-19; (2) Methods: A retrospective cohort study of 1927 hospitalized patients infected with COVID-19 was conducted. Information was gathered on vaccination status, hospitalization episode, and clinical profile of the patients. The effect of vaccination on mortality was analyzed using a multiple logistic regression model, and length of stay was analyzed using linear regression. The performance and fit of the models were evaluated; (3) Results: In hospitalized patients with COVID-19, the risk of dying during admission in vaccinated patients was half that of non-vaccinated (OR: 0.45; CI 95%: 0.25 to 0.84). In patients who were discharged due to improvement, the reduction in hospital stay in vaccinated patients was 3.17 days (CI 95%: 5.88 to 0.47); (4) Conclusions: Patients who, despite having been vaccinated, acquire the infection by SARS-CoV-2, have a significant reduction of the risk of death during admission and a reduction of hospital stay compared with unvaccinated patients.
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