• Mi Re-Unir
    Búsqueda Avanzada
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    Ver ítem 
    •   Inicio
    • RESULTADOS DE INVESTIGACIÓN
    • Artículos Científicos WOS y SCOPUS
    • Ver ítem
    •   Inicio
    • RESULTADOS DE INVESTIGACIÓN
    • Artículos Científicos WOS y SCOPUS
    • Ver ítem

    Endocannabinoid signaling of homeostatic status modulates functional connectivity in reward and salience networks

    Autor: 
    Martín-Pérez, Cristina
    ;
    Contreras-Rodriguez, Oren
    ;
    Pastor, Antoni
    ;
    Christensen, Erynn
    ;
    Andrews, Zane B.
    ;
    de la Torre, Rafael
    ;
    Verdejo-García, Antonio
    Fecha: 
    2022
    Palabra clave: 
    endocannabinoids; resting-state functional connectivity; homeostatic status; hypothalamus; striatum; insula; anterior cingulate cortex; JCR; Scopus
    Revista / editorial: 
    Psychopharmacology
    Tipo de Ítem: 
    Articulo Revista Indexada
    URI: 
    https://reunir.unir.net/handle/123456789/13444
    DOI: 
    https://doi.org/10.1007/s00213-021-05890-z
    Dirección web: 
    https://link.springer.com/article/10.1007/s00213-021-05890-z
    Open Access
    Resumen:
    Rationale Endocannabinoids are well poised to regulate crosstalk between energy sensing of hunger and satiety and reward-driven motivation. Objectives Here, we aimed to unravel associations between plasma endocannabinoids and brain connectivity in homeostatic and reward circuits across hunger and satiety states. Methods Fifteen participants (7 females) underwent two counter-balanced resting-state functional magnetic resonance imaging scans, one after overnight fasting and one after consumption of a standardized filling meal (satiety). Before each scan, we drew blood to measure plasma endocannabinoid concentrations (anandamide [AEA], anandamide-derived POEA, and 2-arachidonoylglycerol [2-AG]), analyzed with liquid chromatography tandem mass spectrometry. Results We found that AEA levels were associated with increased connectivity between the lateral hypothalamus and the ventral striatum during satiety. Furthermore, fasting AEA levels correlated with connectivity between the ventral striatum and the anterior cingulate cortex and the insula. Conclusions Altogether, results suggest that peripheral AEA concentrations are sensitive to homeostatic changes and linked to neural communication in reward and salience networks. Findings may have significant implications for understanding normal and abnormal interactions between homeostatic input and reward valuation.
    Mostrar el registro completo del ítem
    Este ítem aparece en la(s) siguiente(s) colección(es)
    • Artículos Científicos WOS y SCOPUS

    Estadísticas de uso

    Año
    2012
    2013
    2014
    2015
    2016
    2017
    2018
    2019
    2020
    2021
    2022
    2023
    2024
    2025
    Vistas
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    15
    52
    66
    42
    Descargas
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0

    Ítems relacionados

    Mostrando ítems relacionados por Título, autor o materia.

    • Resting-state functional connectivity and socioemotional processes in male perpetrators of intimate partner violence against women 

      Amaoui, Sofia; Martín-Pérez, Cristina; Marin-Morales, A; Bueso-Izquierdo, Natalia; García-León, María Ángeles; Pérez-García, Miguel; Verdejo-Román, Juan (Scientific Reports, 2022)
      Intimate partner violence against women (IPVAW) is a serious and overwhelming public concern. Neuroimaging techniques have provided insights into the brain mechanisms underlying IPVAW perpetration. The purpose of this study ...
    • Social mentalizing in male perpetrators of intimate partner violence against women is associated with resting-state functional connectivity of the Crus II 

      Amaoui, Sofia; Marín-Morales, Agar; Martín-Pérez, Cristina ; Pérez-García, Miguel; Verdejo-Román, Juan (Journal of Psychiatric Research, 2022)
      Social mentalizing refers to the ability to understand the intentions, causes, emotions and beliefs of another person or the self and is crucial for interpersonal understanding. Disturbances in this process may lead to ...
    • Sports in natural environment, sports in urban environment: An fmri study about stress and attention/awareness 

      Baena-Extremera, Antonio; Fuentesal García, Julio; Catena Martínez, Andrés; Martín-Pérez, Cristina (Journal of Sport Science and Medicine, 2021)
      This study aimed to explore, on one side, the differences between a group of athletes exercising outdoor (OG) and another group exercising indoor (IG) in stress and awareness, and, on the other side, between-group differences ...

    Mi cuenta

    AccederRegistrar

    ¿necesitas ayuda?

    Manual de UsuarioContacto: reunir@unir.net

    Listar

    todo Re-UnirComunidades y coleccionesPor fecha de publicaciónAutoresTítulosPalabras claveTipo documentoTipo de accesoEsta colecciónPor fecha de publicaciónAutoresTítulosPalabras claveTipo documentoTipo de acceso






    Aviso Legal Política de Privacidad Política de Cookies Cláusulas legales RGPD
    © UNIR - Universidad Internacional de La Rioja
     
    Aviso Legal Política de Privacidad Política de Cookies Cláusulas legales RGPD
    © UNIR - Universidad Internacional de La Rioja