Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity
Autor:
Guallar, María Pilar
; Meiriño, Rosa
; Donat-Vargas, Carolina
; Jouvé, Nicolás
; Soriano, Vicente
Fecha:
08/2020Palabra clave:
Revista / editorial:
International Journal of Infectious DiseasesTipo de Ítem:
Articulo Revista IndexadaResumen:
A relationship between the infecting dose and the risk of disease severity has not been demonstrated for SARS-CoV-2 infection. Here, we report three clusters of individuals that were potentially exposed to distinct inoculum in Madrid. Overall each group developed divergent clinical forms of COVID-19. Our data support that a greater viral inoculum at the time of SARS-CoV-2 exposure might determine a higher risk of severe COVID-19.
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