• Mi Re-Unir
    Búsqueda Avanzada
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    Ver ítem 
    •   Inicio
    • RESULTADOS DE INVESTIGACIÓN
    • Artículos Científicos WOS y SCOPUS
    • Ver ítem
    •   Inicio
    • RESULTADOS DE INVESTIGACIÓN
    • Artículos Científicos WOS y SCOPUS
    • Ver ítem

    A cluster-analytic profiling of heroin-dependent patients based on level, clinical adequacy, and patient-desired adjustment of buprenorphine dosage during buprenorphine-naloxone maintenance treatment in sixteen Spanish centers

    Autor: 
    Alcaraz, Saul
    ;
    González-Saiz, Francisco
    ;
    Trujols, Joan
    ;
    Vergara-Moragues, Esperanza
    ;
    Sinol, Nuria
    ;
    Pérez de los Cobos, José
    Fecha: 
    2018
    Palabra clave: 
    buprenorphine-naloxone treatment; heroin dependence; dosage management; cluster analysis; treatment outcomes; JCR; Scopus
    Revista / editorial: 
    Drug and Alcohol Dependence
    Tipo de Ítem: 
    Articulo Revista Indexada
    URI: 
    https://reunir.unir.net/handle/123456789/6764
    DOI: 
    https://doi.org/10.1016/j.drugalcdep.2018.02.020
    Dirección web: 
    https://www.ncbi.nlm.nih.gov/pubmed/29702336
    Resumen:
    Background: Buprenorphine dosage is a crucial factor influencing outcomes of buprenorphine treatment for heroin use disorders. Therefore, the aim of the present study is to identify naturally occurring profiles of heroin-dependent patients regarding individualized management of buprenorphine dosage in clinical practice of buprenorphine-naloxone maintenance treatment. Methods: 316 patients receiving buprenorphine-naloxone maintenance treatment were surveyed at 16 Spanish centers during the stabilization phase of this treatment. Patients were grouped using cluster analysis based on three key indicators of buprenorphine dosage management: dose, adequacy according to physician, and adjustment according to patient. The clusters obtained were compared regarding different facets of patient clinical condition. Results: Four clusters were identified and labeled as follows (buprenorphine average dose and percentage of participants in each cluster are given in brackets): "Clinically Adequate and Adjusted to Patient Desired Low Dosage" (2.60 mg/d, 37.05%); "Clinically Adequate and Adjusted to Patient Desired High Dosage" (10.71 mg/d, 29.18%); "Clinically Adequate and Patient Desired Reduction of Low Dosage" (3.38 mg/d, 20.0%); and "Clinically Inadequate and Adjusted to Patient Desired Moderate Dosage" (7.55 mg/d, 13.77%). Compared to patients from the other three clusters, participants in the latter cluster reported more frequent use of heroin and cocaine during last week, lower satisfaction with buprenorphine-naloxone as a medication, higher prevalence of buprenorphine-naloxone adverse effects and poorer psychological adjustment. Conclusions: Our results show notable differences between clusters of heroin-dependent patients regarding buprenorphine dosage management. We also identified a group of patients receiving clinically inadequate buprenorphine dosage, which was related to poorer clinical condition.
    Mostrar el registro completo del ítem
    Este ítem aparece en la(s) siguiente(s) colección(es)
    • Artículos Científicos WOS y SCOPUS

    Estadísticas de uso

    Año
    2012
    2013
    2014
    2015
    2016
    2017
    2018
    2019
    2020
    2021
    2022
    2023
    2024
    2025
    Vistas
    0
    0
    0
    0
    0
    0
    38
    144
    80
    64
    86
    68
    75
    83
    Descargas
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0

    Ítems relacionados

    Mostrando ítems relacionados por Título, autor o materia.

    • Towards a common metric for assessing heroin-dependent patient satisfaction with medications: Testing methadone and buprenorphine-naloxone 

      Pérez de los Cobos, José; Alcaraz, Saul; Sinol, Nuria; González-Saiz, Francisco; Vergara-Moragues, Esperanza (Drug and Alcohol Dependence, 07/2020)
      Background: Patient satisfaction with methadone or buprenorphine-naloxone can be multidimensionally and specifically assessed by using, respectively, the Scale to Assess Satisfaction with Medications for Addiction ...
    • Patient-reported side effects of buprenorphine-naloxone: identifying independent predictors from patient views and clinical assessment during maintenance treatment of heroin use disorder 

      Pérez de los Cobos, José; Alcaraz, Saul; Trujols, Joan; Sinol, Nuria; Vergara-Moragues, Esperanza ; González Saiz, Francisco (Value in health, 2018)
      To identify the factors independently associated with patient-reported side effects of buprenorphine/naloxone (B/N) tablets. METHODS: 313 heroindependent patients receiving B/N maintenance treatment at least for the last ...
    • Can symptoms help in differential diagnosis between substance-induced vs independent psychosis in adults with a lifetime diagnosis of cocaine use disorder? 

      Vergara-Moragues, Esperanza ; Mestre-Pintó, Joan I; Araos, Pedro; Rodríguez-Fonseca, Fernando; González-Saiz, Francisco (Psychiatry Research, 08/2016)
      The main goal of this study it is explore the psychopathological differences between IPD and SIPD in a sample of 125 adults with a lifetime diagnosis of cocaine disorder recruited from treatment setting and through street ...

    Mi cuenta

    AccederRegistrar

    ¿necesitas ayuda?

    Manual de UsuarioContacto: reunir@unir.net

    Listar

    todo Re-UnirComunidades y coleccionesPor fecha de publicaciónAutoresTítulosPalabras claveTipo documentoTipo de accesoEsta colecciónPor fecha de publicaciónAutoresTítulosPalabras claveTipo documentoTipo de acceso






    Aviso Legal Política de Privacidad Política de Cookies Cláusulas legales RGPD
    © UNIR - Universidad Internacional de La Rioja
     
    Aviso Legal Política de Privacidad Política de Cookies Cláusulas legales RGPD
    © UNIR - Universidad Internacional de La Rioja