• A Comparison Between Recombinant Listeria GAPDH Proteins and GAPDH Encoding mRNA Conjugated to Lipids as Cross-Reactive Vaccines for Listeria, Mycobacterium, and Streptococcus 

      Teran-Navarro, Héctor; Salcines-Cuevas, David; Calderón-González, Ricardo; Tobes, Raquel; Calvo-Montes, Jorge; Pérez-Del Molino Bernal, Inmaculada Concepción; Yánez-Díaz, Sonsoles; Fresno, Manuel; Álvarez-Domínguez, Carmen (1) (Frontiers in immunology, 2021)
      Cross-reactive vaccines recognize common molecular patterns in pathogens and are able to confer broad spectrum protection against different infections. Antigens common to pathogenic bacteria that induce broad immune ...
    • Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase 

      Álvarez-Domínguez, Carmen (1); Salcines-Cuevas, David; Teran-Navarro, Héctor; Calderón-González, Ricardo; Tobes, Raquel; García, Isabel; Grijalvo, Santiago; Paradela, Alberto; Seoane, Asunción; Sangari, Felix J.; Fresno, Manuel; Calvo-Montes, Jorge; Pérez Del Molino Bernal, I. Concepción; Yañez-Diaz, Sonsoles (Frontiers in Cellular and Infection Microbiology, 10/2020)
      The glycolytic enzyme and bacterial virulence factor of Listeria monocytogenes, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH, Lmo2459), ADP-ribosylated the small GTPase, Rab5a, and blocked phagosome maturation. This ...
    • Mecanismos moleculares y manejo clínico de la tuberculosis resistente a fármacos: ¿Un enemigo invencible? 

      Vera Ramírez, Keyla María; Dávila Morocho, Maryuri Jessenia; Gusqui Gusqui, Iván Marcelo; Anguisaca Castillo, Kimberly Ivanova; López Lalangui, Mayra Alexandra; Guartizaca Durán, Vanessa Alexandra; Morales Carrasco, Alex Patricio (1) (Archivos Venezolanos de Farmacologia y Terapeutica, 2019)
      La Tuberculosis resistente a fármacos es un problema de salud pública mundial y es uno de los principales obstáculos para alcanzar los objetivos de control planteados a nivel global, ocasionando peores resultados clínicos ...
    • Trends in hospitalizations and deaths in HIV-infected patients in Spain over two decades 

      Ramos-Rincón, José-Manuel; Menchi-Elanzi, Maroune; Pinargote-Celorio, Héctor; Mayoral, Asunción; González-Alcaide, Gregorio; de Mendoza, Carmen; Barreiro, Pablo; Gómez-Gallego, Felix (1); Corral, Octavio Jorge (1); Soriano, Vicente (1) (AIDS, 02/2022)
      Background: The prognosis of HIV infection dramatically improved after the introduction of triple antiretroviral therapy 25 years ago. Herein, we report the impact of further improvements in HIV management since then, ...