• Hepatitis delta in patients with resolved hepatitis B virus infection 

      Aguilera, Antonio; Rodríguez-Calviño, Javier; Mendoza, Carmen de; Soriano, Vicente (European Journal of Gastroenterology & Hepatology, 09/2018)
      Background The hepatitis delta virus (HDV) causes the most aggressive form of chronic viral hepatitis. As HDV replication requires hepatitis B virus (HBV), HDV screening is limited to HBsAg+ carriers. To date, individuals ...
    • Occult hepatitis B and HIV infection 

      Soriano, Vicente ; Aguilera, Antonio; González, Rocío; Gómez-Gallego, Felix ; Barea, Luisa; Treviño, Mercedes; Corral, Octavio Jorge (European Journal of Gastroenterology & Hepatology, 11/2019)
      Introduction Occult hepatitis B virus (HBV) infection, so-called occult B infection (OBI), is defined by the recognition of HBV-DNA in the absence of serum hepatitis B surface antigen (HBsAg). The HBV-DNA genome in OBI is ...
    • Overt and occult hepatitis B among immigrants and native blood donors in Madrid, Spain 

      González, Rocío; Barea, Luisa; Arruga, Ana; Richart, Alberto; Soriano, Vicente (Therapeutic Advances in Infectious Disease, 12/2020)
      Background: The risk of transfusion-transmitted viral infections is very low in developed countries. Recent massive migration flows from highly hepatitis B virus (HBV), hepatitis C virus (HCV) and/or HIV endemic regions ...
    • Pre-Exposure Prophylaxis for viral infections other than HIV 

      Soriano, Vicente; Treviño, Ana; de Mendoza, Carmen; Moreno-Torres, Víctor; Pintos, Ilduara; Barreiro, Pablo; Corral, Octavio Jorge (Infezioni in Medicina, 2022)
      The battle against human viral infections has histori-cally relied on two medical strategies, namely vaccines to protect from contagion and antivirals to treat infected patients. In the absence of vaccines, antivirals have ...
    • Prevalence and incidence of hepatitis delta in patients with chronic hepatitis B in Spain 

      Aguilera, Antonio; Trastoy, Rocío; Rodríguez-Calviño, Javier; Manso, Tamara; Mendoza, Carmen de; Soriano, Vicente (European Journal of Gastroenterology & Hepatology, 09/2018)
      Background Hepatitis delta virus (HDV) is a defective agent that only replicates in the presence of the hepatitis B virus. Accordingly, HDV acquisition may occur as superinfection of HBsAg+ carriers or following acute dual ...
    • The unexpected high prevalence of HBV subgenotype D4 in patients with chronic hepatitis B in Galicia, a northwestern Spanish region, reflects strong links with Latin America 

      Trastoy, Rocío; González-Alba, José María; Soriano, Vicente ; Rodríguez-Calviño, José Javier; de Mendoza, Carmen; Costa, José Javier; Cea, María; Barbeito, Gema; Corral, Octavio Jorge ; Gómez-Gallego, Felix ; Pérez del Molino, María Luisa; Carlos Galán, Juan; Aguilera, Antonio (Journal of Clinical Virology, 2022)
      Background: Hepatitis B virus (HBV) comprises 9 genotypes and multiple subgenotypes that depict differences in geographic distribution, clinical outcome and response to antiviral therapy. However, the molecular epidemiology ...
    • Ultra-long-acting (XLA) antivirals for chronic viral hepatitis 

      Soriano, Vicente ; Alvarez, Carmen ; Edagwa, Benson; de Mendoza, Carmen; Montoya, Noemí ; Treviño, Ana ; Gendelman, Howard E. (Elsevier B.V., 2022)
      Viral hepatitis is among the top four causes of mortality globally, causing 1.4 million deaths each year, exceeding tuberculosis, malaria and human immunodeficiency virus. Hepatitis B and C are responsible for 90% of ...