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Mostrando ítems 11-20 de 48
Tough requirements for new antiretroviral drugs
(The Lancet HIV, 2020-03)
Medical and social attention to HIV infection has declined globally and is increasingly focused on developing regions, where the epidemic is still largely uncontrolled. In North America and western Europe, AIDS is rarely ...
Hepatitis delta in patients hospitalized in Spain (1997-2018)
(NLM (Medline), 2021)
BACKGROUND: Hepatitis delta is the most aggressive form of chronic viral hepatitis. We examined the clinical burden, epidemiological features and time trends for hepatitis delta patients hospitalized in Spain during the ...
Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity
(International Journal of Infectious Diseases, 2020-08)
A relationship between the infecting dose and the risk of disease severity has not been demonstrated for SARS-CoV-2 infection. Here, we report three clusters of individuals that were potentially exposed to distinct inoculum ...
Trends in hospitalizations and deaths in HIV-infected patients in Spain over two decades
(AIDS, 2022-02)
Background: The prognosis of HIV infection dramatically improved after the introduction of triple antiretroviral therapy 25 years ago. Herein, we report the impact of further improvements in HIV management since then, ...
Short Communication: Impact of COVID-19 on Case Reporting for HTLV and HIV-2 in Spain
(Mary Ann Liebert Inc., 2021)
The medical demand imposed by COVID-19 has distracted proper care of other illnesses. Herein, we report the impact on new diagnoses of HTLV-1, HTLV-2, and HIV-2 in Spain, where these infections are mostly driven by immigration ...
Impact of scaling up SARS-CoV-2 vaccination on COVID-19 hospitalizations in Spain
(Elsevier B.V., 2021)
Background: The advent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines has been associated with a significant decline in coronavirus disease 2019 (COVID-19) hospitalizations and deaths. However, ...
Envisioning a hepatitis delta cure with new antivirals
(Future Medicine Ltd., 2021)
Envisioning a hepatitis delta cure with new antivirals
Ultra-long-acting antivirals as chemical vaccines to prevent viral diseases
(Future Microbiology, 2022-07)
For two centuries, vaccines have been successful in the fight against viruses, triggering immune protection. Indeed, the elimination of smallpox, the only infectious disease eradicated to date, was made possible through ...
A greater virulent HIV-1 subtype B variant has circulated in The Netherlands since the 1990’s
(AIDS Reviews, 2022)
Despite being COVID-19 the global focus of attention nowadays, other pandemics caused by RNA viruses are ongoing. This is the case for AIDS. Roughly, 38 million people are, at present, living with HIV-1 infection worldwide ...
Oral antivirals for the prevention and treatment of SARS-CoV-2 infection
(AIDS Reviews, 2022)
Vaccines and antivirals are the classical weapons deployed to contain, prevent, and treat life-threatening
viral illnesses. Specifically, for SARS-CoV-2 infection, vaccines protect against severe COVID-19 disease
manifestations ...