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Jerome Lejeune passed away 25 years ago
(Hereditas, 2019-06-06)
During the past 60 years, modern genetics has steadily evolved from diagnostics to therapeutics. However, treatment of genetic disorders is still in its infancy, with the advent of genome editing as its greatest promise.
Hepatitis Delta Could Be More Frequent than Previously Thought
(AIDS Reviews, 2018-10)
HDV is a unique defective agent that only infects humans and requires the presence of hepatitis B to complete its life replication cycle within hepatocytes.
HTLV-1 Infection is Rising Up in Spain Whereas HTLV-2 is Vanishing
(AIDS Reviews, 2019-10)
Infection with human retroviruses is responsible for global epidemics and significant morbidity and mortality worldwide. The current global estimates of infected people are 38 million for HIV-1, 1-2 million for HIV-2, 10 ...
Antiretroviral Therapy for HIV-2 Infection in Non-Endemic Regions
(AIDS Reviews, 2020-01)
Human immunodeficiency virus type 2 (HIV-2) was isolated in AIDS patients in 1986. Around 1-2 million people are infected worldwide. The virus is less transmissible than HIV-1, being sexual contacts the most frequent route ...
Why Not an Opioid Epidemic in Europe Like in the USA?
(AIDS Reviews, 2019-12)
The CDC reported 70,237 drug overdose deaths in the United States in 2017 (Scholl et al., MMWR 2018; 67: 1419-27). Sadly, this yearly rate has been increasing significantly during the past two decades. Opioids, mostly ...
Rebound in Sexually Transmitted Infections Following the Success of Antiretrovirals for HIV/AIDS
(AIDS Reviews, 2018-10)
Nearly 1 million people become infected every day with any of the four major curable sexually transmitted infections (STIs), namely trichomoniasis, chlamydia, gonorrhea, and syphilis. Despite huge global incidence, STIs ...
Clinical Presentation of Individuals With Human T-Cell Leukemia Virus Type-1 Infection in Spain
(Open Forum Infectious Diseases, 2019-02)
Background. Although only 8%-10% of persons infected with human T-cell leukemia virus type 1 (HTLV-1) may develop virus-associated diseases lifelong, misdiagnosis of asymptomatic infected carriers frequently leads to late ...
HIV co-infection in HTLV-1 carriers in Spain
(Virus Research, 2019-06)
Background: Human retroviruses HIV and HTLV share transmission routes. HIV widely spread in Spain during the 80 s through injection drug use and sex, and nowadays HIV rates in Spain account for one of the largest in Europe. ...
Clinical experience with integrase inhibitors in HIV-2-infected individuals in Spain
(Journal of Antimicrobial Chemotherapy, 2019-05)
Background: HIV-2 is a neglected virus despite estimates of 1-2 million people being infected worldwide. The virus is naturally resistant to some antiretrovirals used to treat HIV-1 and therapeutic options are limited for ...
Sexually Transmitted Infections in Men having Sex with Men - Rising Numbers and Wider Etiologies
(AIDS Reviews, 2019-01)
Classical sexually transmitted infections (STI), namely, syphilis, gonorrhea, trichomonas, and chlamydia, are on the rise worldwide.