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dc.contributor.authorBenito, Rafael
dc.contributor.authorGil, Joaquina
dc.contributor.authorSahagún, Juan
dc.contributor.authorSoriano, Vicente
dc.date2021
dc.date.accessioned2021-07-12T12:02:00Z
dc.date.available2021-07-12T12:02:00Z
dc.identifier.issn0041-1345
dc.identifier.urihttps://reunir.unir.net/handle/123456789/11596
dc.description.abstractBackground Frequent and rapid development of myelopathy has been reported in individuals with human T-lymphotropic virus type 1 (HTLV-1) infection following solid organ transplantation. There is no information regarding HTLV-2, a closely related virus that often infects injection drug users. Methods This study includes a retrospective analysis of all consecutive organ transplants performed during the last 2 decades at a large reference transplantation unit in Spain. All participants were tested for anti-HTLV antibodies. Results A total of 2019 individuals were tested for HTLV during the study period, including 663 potential donors and 1356 recipient candidates. Twelve (0.59%) were reactive on initial HTLV serologic screening, but only 6 (all recipients) were confirmed as positive, all for HTLV-2. Two recipients underwent liver transplantation and have remained asymptomatic despite being on tacrolimus for 4 and 8 years, respectively. Likewise, the remaining 4 HTLV-2 carriers have not developed clinical complications potentially associated with HTLV-2. Conclusions Unlike HTLV-1 infection, HTLV-2 infection in the transplantation setting does not seem to be associated with rapid development of neurologic complications, Given the cross-seroreactivity between HTLV-1 and HTLV-2, discriminatory rapid tests are urgently needed and would reduce unnecessary organ discharge.es_ES
dc.language.isoenges_ES
dc.publisherTransplantation proceedingses_ES
dc.relation.ispartofseries;vol. 53, nº 2
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S0041134520326944?via%3Dihubes_ES
dc.rightsopenAccesses_ES
dc.subjecthuman T-Lymphotropic virus type 2es_ES
dc.subjectorgan transplantationes_ES
dc.subjectScopuses_ES
dc.subjectWOS(2)es_ES
dc.titleClinical Outcome in Human T-Lymphotropic Virus Type 2 Carriers Following Organ Transplantationes_ES
dc.typeArticulo Revista Indexadaes_ES
reunir.tag~ARIes_ES
dc.identifier.doihttps://doi.org/10.1016/j.transproceed.2020.08.029


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