OBJECTIVE: To examine the clinical burden and disease spectrum, as well as time trends for human T-cell leukemia virus type 1 (HTLV-1) and HTLV type 2 (HTLV-2) hospital admissions. DESIGN: Retrospective, observational study ...

A relationship between the infecting dose and the risk of disease severity has not been demonstrated for SARS-CoV-2 infection. Here, we report three clusters of individuals that were potentially exposed to distinct inoculum ...

Nanoformulations of cabotegravir prodrugs have been developed to prolong the pharmacokinetics of the antiretroviral agent. They can be present in the plasma of mice and non-human primates for a year following a single injection.

Despite the availability of both effective preventive vaccines and oral antivirals, over 250 million people are chronically infected with the hepatitis B virus (HBV). Globally, chronic hepatitis B is the leading cause of ...

Background: The risk of transfusion-transmitted viral infections is very low in developed countries. Recent massive migration flows from highly hepatitis B virus (HBV), hepatitis C virus (HCV) and/or HIV endemic regions ...

The current global crisis produced by the SARS-CoV-2 pandemic is unprecedented. Even the 1918 influenza pandemic (Spanish flu) did not halt the planet so abruptly and deeply as it ran during World War I.

COVID-19 is rapidly expanding globally, with more than 1,800,000 cases and 105,000 deaths to date (April 11, 2020) (www.worldometers.info). The WHO upgrade to pandemic, the emergency declaration in the United States, and ...

The recent emergence of a novel coronavirus (severe acute respiratory syndrome coronavirus 2) has caused a pandemic, which is the most severe infectious disease outbreak in many decades. Other infective agents such as ...

COVID-19, caused by SARS-CoV-2, continues to be a major health problem since its first description in Wuhan, China, in December 2019. Multiple drugs have been tried to date in the treatment of COVID-19. Critical to treatment ...

La familia Retroviridae incluye 7 subfamilias. Los miembros de 2 de ellas infectan a humanos y son patogénicos. Se trata de los deltarretrovirus, de los cuales el human T-cell lymphotropic virus (HTLV, «virus linfotrópico ...