Mostrando ítems 31-40 de 53
Hospital admissions in individuals with HTLV-1 infection in Spain
OBJECTIVE: To examine the clinical burden and disease spectrum, as well as time trends for human T-cell leukemia virus type 1 (HTLV-1) and HTLV type 2 (HTLV-2) hospital admissions. DESIGN: Retrospective, observational study ...
Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity
(International Journal of Infectious Diseases, 2020-08)
A relationship between the infecting dose and the risk of disease severity has not been demonstrated for SARS-CoV-2 infection. Here, we report three clusters of individuals that were potentially exposed to distinct inoculum ...
Long-acting antiretroviral therapy
(Nature Materials, 2020-08-01)
Nanoformulations of cabotegravir prodrugs have been developed to prolong the pharmacokinetics of the antiretroviral agent. They can be present in the plasma of mice and non-human primates for a year following a single injection.
Advances in hepatitis B therapeutics
(Therapeutic Advances in Infectious Disease, 2020-10)
Despite the availability of both effective preventive vaccines and oral antivirals, over 250 million people are chronically infected with the hepatitis B virus (HBV). Globally, chronic hepatitis B is the leading cause of ...
Overt and occult hepatitis B among immigrants and native blood donors in Madrid, Spain
(Therapeutic Advances in Infectious Disease, 2020-12)
Background: The risk of transfusion-transmitted viral infections is very low in developed countries. Recent massive migration flows from highly hepatitis B virus (HBV), hepatitis C virus (HCV) and/or HIV endemic regions ...
Why such excess of mortality for COVID-19 in Spain?
(Therapeutic Advances in Infectious Disease, 2020-06)
The current global crisis produced by the SARS-CoV-2 pandemic is unprecedented. Even the 1918 influenza pandemic (Spanish flu) did not halt the planet so abruptly and deeply as it ran during World War I.
Keeping alive enterprises while embracing unprecedented COVID-19 restrictions
(Therapeutic Advances in Infectious Disease, 2020-04)
COVID-19 is rapidly expanding globally, with more than 1,800,000 cases and 105,000 deaths to date (April 11, 2020) (www.worldometers.info). The WHO upgrade to pandemic, the emergency declaration in the United States, and ...
Coronavirus and other airborne agents with pandemic potential
(Current opinion in environmental science and health, 2020)
The recent emergence of a novel coronavirus (severe acute respiratory syndrome coronavirus 2) has caused a pandemic, which is the most severe infectious disease outbreak in many decades. Other infective agents such as ...
The Importance of Understanding the Stages of COVID-19 in Treatment and Trials
(AIDS reviews, 2021)
COVID-19, caused by SARS-CoV-2, continues to be a major health problem since its first description in Wuhan, China, in December 2019. Multiple drugs have been tried to date in the treatment of COVID-19. Critical to treatment ...
Situación epidemiológica actual de la infección por VIH-2 y HTLV-1 en España
(Medicina clinica, 2021)
La familia Retroviridae incluye 7 subfamilias. Los miembros de 2 de ellas infectan a humanos y son patogénicos. Se trata de los deltarretrovirus, de los cuales el human T-cell lymphotropic virus (HTLV, «virus linfotrópico ...