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Determinants of poor clinical outcome in patients with influenza pneumonia: A systematic review and meta-analysis
(International Journal of Infectious Diseases, 2023)
Background: The clinical burden of influenza is increasing worldwide. Aging, immunosuppression, and underlying respiratory illness are determinants of poor clinical outcomes, including greater mortality. Bacterial infections ...
Providing Spiritual Care to In-Hospital Patients During COVID-19: A Preliminary European Fact-Finding Study
(Journal of Religion & Health, 2022)
Historically, there has be a close relationship between the nursing services and spiritual care provision to patients, arising due to the evolvement of many hospitals and nursing programmes from faith-based institutions ...
Ultra-long-acting (XLA) antivirals for chronic viral hepatitis
(Elsevier B.V., 2022)
Viral hepatitis is among the top four causes of mortality globally, causing 1.4 million deaths each year, exceeding tuberculosis, malaria and human immunodeficiency virus. Hepatitis B and C are responsible for 90% of ...
Testing a vaccine candidate against Hepatitis C virus designed by combinatorial optimization
(Scientific Reports, 2023)
This paper presents a new procedure for vaccine design against highly variable viruses such as Hepatitis C. The procedure uses an optimization algorithm to design vaccines that maximize the coverage of epitopes across ...
Triple Threat: HDV, HBV, HIV Coinfection
(Clinics in Liver Disease, 2023)
First discovered in the late 1970s, hepatitis delta virus (HDV) has emerged as an important driver of decompensated liver disease and hepatocellular carcinoma (HCC) worldwide. HDV requires hepatitis B virus (HBV) for ...
Advances in long-acting slow effective release antiretroviral therapies for treatment and prevention of HIV infection
(Advanced Drug Delivery Reviews, 2023)
Adherence to daily oral antiretroviral therapy (ART) is a barrier to both treatment and prevention of human immunodeficiency virus (HIV) infection. To overcome limitations of life-long daily regimen adherence, longacting ...
Predictors of in-hospital mortality in HIV-infected patients with COVID-19
(QJM: An International Journal of Medicine, 2023)
Background Underlying immunodeficiency is associated with severe COVID-19, but the prognosis of persons with human immunodeficiency virus (HIV) (PWH) with COVID-19 is under debate. Aim: assessment of the mortality rate and ...