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Mostrando ítems 101-109 de 109
Ultra-long-acting (XLA) antivirals for chronic viral hepatitis
(Elsevier B.V., 2022)
Viral hepatitis is among the top four causes of mortality globally, causing 1.4 million deaths each year, exceeding tuberculosis, malaria and human immunodeficiency virus. Hepatitis B and C are responsible for 90% of ...
Testing a vaccine candidate against Hepatitis C virus designed by combinatorial optimization
(Scientific Reports, 2023)
This paper presents a new procedure for vaccine design against highly variable viruses such as Hepatitis C. The procedure uses an optimization algorithm to design vaccines that maximize the coverage of epitopes across ...
Triple Threat: HDV, HBV, HIV Coinfection
(Clinics in Liver Disease, 2023)
First discovered in the late 1970s, hepatitis delta virus (HDV) has emerged as an important driver of decompensated liver disease and hepatocellular carcinoma (HCC) worldwide. HDV requires hepatitis B virus (HBV) for ...
Advances in long-acting slow effective release antiretroviral therapies for treatment and prevention of HIV infection
(Advanced Drug Delivery Reviews, 2023)
Adherence to daily oral antiretroviral therapy (ART) is a barrier to both treatment and prevention of human immunodeficiency virus (HIV) infection. To overcome limitations of life-long daily regimen adherence, longacting ...
Current Challenges for Conscientious Objection by Physicians in Spain
(Linacre Quarterly, 2023)
The College of Physicians of Madrid organized an open debate on conscientious objection (CO) in the medical profession on September 14, 2022. We summarize here the main arguments discussed. CO is defined as the right to ...
The use of 'sex' and 'gender' in medical research
(Journal Contents, 2023)
There is a widespread practice of using ‘sex’ and ‘gender’ interchangeably. The World Health Organization considers that they are not. It defines sex as a set of chromosome-dependent biological variables that show unique ...
Mental health crisis in the youth and rebound in sexually transmitted infections
(AIDS reviews, 2023)
There is a crisis of emotional well-being and mental health in adolescents and young people in developed countries (Piao et al. Eur Child Adolesc Psychiatry 2022; 31: 1827-45). Although the COVID-19 pandemic has unveiled ...
Predictors of in-hospital mortality in HIV-infected patients with COVID-19
(QJM: An International Journal of Medicine, 2023)
Background Underlying immunodeficiency is associated with severe COVID-19, but the prognosis of persons with human immunodeficiency virus (HIV) (PWH) with COVID-19 is under debate. Aim: assessment of the mortality rate and ...
Adult T-cell leukemia/lymphoma in HTLV-1 non-endemic regions
(Journal of Clinical Virology, 2023)
Background: HTLV-1 infection is a neglected disease, despite producing neurological and lymphoproliferative severe illnesses and affect over 10 million people worldwide. Roughly 5% of HTLV-1 carriers develop Adult T-cell ...