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    • A Comparison Between Recombinant Listeria GAPDH Proteins and GAPDH Encoding mRNA Conjugated to Lipids as Cross-Reactive Vaccines for Listeria, Mycobacterium, and Streptococcus 

      Teran-Navarro, Héctor; Salcines-Cuevas, David; Calderón-González, Ricardo; Tobes, Raquel; Calvo-Montes, Jorge; Pérez-Del Molino Bernal, Inmaculada Concepción; Yañez-Diaz, Sonsoles; Fresno, Manuel; Álvarez-Domínguez, Carmen (Frontiers in immunology, 2021)
      Cross-reactive vaccines recognize common molecular patterns in pathogens and are able to confer broad spectrum protection against different infections. Antigens common to pathogenic bacteria that induce broad immune ...

    • Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase 

      Álvarez-Domínguez, Carmen ; Salcines-Cuevas, David; Teran-Navarro, Héctor; Calderón-González, Ricardo; Tobes, Raquel; García, Isabel; Grijalvo, Santiago; Paradela, Alberto; Seoane, Asunción; Sangari, Felix J.; Fresno, Manuel; Calvo-Montes, Jorge; Pérez Del Molino Bernal, I. Concepción; Yañez-Diaz, Sonsoles (Frontiers in Cellular and Infection Microbiology, 10/2020)
      The glycolytic enzyme and bacterial virulence factor of Listeria monocytogenes, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH, Lmo2459), ADP-ribosylated the small GTPase, Rab5a, and blocked phagosome maturation. This ...

    • Glyceraldehyde-3-phosphate dehydrogenase common peptides of listeria monocytogenes, mycobacterium marinum and streptococcus pneumoniae as universal vaccines 

      Salcines-Cuevas, David; Teran-Navarro, Héctor; Calderón-González, Ricardo; Torres-Rodriguez, Paula; Tobes, Raquel; Fresno, Manuel; Calvo-Montes, Jorge; Pérez Del Molino-Bernal, Concepción; Yañez-Diaz, Sonsoles; Álvarez-Domínguez, Carmen (Vaccines, 2021)
      Universal vaccines can be prepared with antigens common to different pathogens. In this regard, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a common virulence factor among pathogenic bacteria of the genera ...

    • Impact of immunosuppression on Listeria monocytogenes infection in Spain 

      Vázquez, Elena; de Gregorio, Óscar; Álvarez, Carmen; Soriano, Vicente; Corral, Octavio; Ortega-de la Puente, Alfonso; de la Cruz-Echeandía, Marina; Blanco-Valencia, Xiomara Patricia; Royuela, Ana; Martín-Portugués, Mario; Esteban-Sampedro, Jorge; Moreno-Torres, Víctor (Pathogens and Global Health, 2025)
      Introduction Immunosuppression (IS) determines a higher risk of disease severity from Listeria monocytogenes (LM) infection. Methods We examined the epidemiology of IS in all patients hospitalized with LM in Spain ...

    • Increased incidence and mortality from Listeria monocytogenes infection in Spain 

      Vázquez, Elena; de Gregorio-Vicente, Óscar; Soriano, Vicente; Álvarez-Domínguez, Carmen; Corral, Octavio; Moreno-Torres, Víctor (International Journal of Infectious Diseases, 2024)
      Objectives Listeria monocytogenes (LM) is a health threat worldwide given its high mortality and the growing of high-risk susceptible populations. Methods All hospitalizations with a diagnosis of LM in the National ...

    • Pregnancy-related listeriosis in Spain 

      Vázquez, Elena; de Gregorio, Óscar; Soriano, Vicente; Álvarez, Carmen; Ortega-de la Puente, Alfonso; de la Cruz-Echeandía, Marina; Blanco-Valencia, Xiomara Patricia; Royuela, Ana; Esteban-Sampedro, Jorge; Martín-Portugués, Mario; Corral, Octavio; Moreno-Torres, Víctor (Journal of Infection and Public Health, 2025)
      Background Pregnant women are at high risk of acquiring listeriosis, resulting in severe fetal and neonatal outcomes. Methods All hospitalizations with a listeriosis diagnosis in pregnant women (obstetric listeriosis) ...