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Listar por tema "integrase inhibitors"

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    • Antiretroviral Therapy for HIV-2 Infection in Non-Endemic Regions 

      Mendoza, Carmen de; Lozano, A. B.; Caballero, Estrella; Cabezas, Teresa; Ramos, José M.; Soriano, Vicente ; Spanish HIV-2 Network (AIDS Reviews, 01/2020)
      Human immunodeficiency virus type 2 (HIV-2) was isolated in AIDS patients in 1986. Around 1-2 million people are infected worldwide. The virus is less transmissible than HIV-1, being sexual contacts the most frequent route ...

    • Expanded Spectrum of Antiretroviral-Selected Mutations in Human Immunodeficiency Virus Type 2 

      Tzou, Philip L.; Descamps, Diáne; Rhee, Soo-Yon; Raugi, Dana N; Charpentier, Charlotte; Taveira, Nuno; Smith, Robert A; Soriano, Vicente ; Mendoza, Carmen de; Holmes, Susan; Gottlieb, Geoffrey S.; Shafer, Robert W. (Journal of Infectious Diseases, 06/2020)
      Background: HIV-1 and HIV-2 differ in their antiretroviral (ARV) susceptibilities and drug resistance mutations (DRMs). Methods: We analyzed published HIV-2 pol sequences to identify HIV-2 treatment-selected mutations ...