Listar por tema "Sigma-1 receptor"

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Sigma-1 Receptors Control Neuropathic Pain and Peripheral Neuroinflammation After Nerve Injury in Female Mice: A Transcriptomic Study

Ruiz-Cantero, M. Carmen; Entrena, José M.; Artacho-Cordón, Antonia; Huerta, Miguel Á.; Portillo-Salido, Enrique; Nieto, Francisco R.; Baeyens, José M.; Costigan, Michael; González-Cano, Rafael; Cobos, Enrique J. (Journal of Neuroimmune Pharmacology, 2024)

The mechanisms for neuropathic pain amelioration by sigma-1 receptor inhibition are not fully understood. We studied genome-wide transcriptomic changes (RNAseq) in the dorsal root ganglia (DRG) from wild-type and sigma-1 ...