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Listar por autor "Pérez-Santín, Efrén"
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Applicability domains of neural networks for toxicity prediction
Pérez-Santín, Efrén; de-la-Fuente-Valentín, Luis; González García, Marian; Segovia Bravo, Kharla Andreina; López Hernández, Fernando Carlos; López Sánchez, José Ignacio (AIMS Mathematics, 2023)In this paper, the term “applicability domain” refers to the range of chemical compounds for which the statistical quantitative structure-activity relationship (QSAR) model can accurately predict their toxicity. This is a ... -
Pneumolysin as a target for new therapies against pneumococcal infections: A systematic review
Cima-Cabal, María Dolores; Molina, Felipe; López-Sánchez, José Ignacio; Pérez-Santín, Efrén; García-Suárez, María del Mar (PLoS ONE, 2023)Background This systematic review evaluates pneumolysin (PLY) as a target for new treatments against pneumococcal infections. Pneumolysin is one of the main virulence factors produced by all types of pneumococci. This toxin ...