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Mostrando ítems 1-20 de 20

    • An Interplay between Oxidative Stress (Lactate Dehydrogenase) and Inflammation (Anisocytosis) Mediates COVID-19 Severity Defined by Routine Clinical Markers 

      Alonso-Bernáldez, Marta; Cuevas-Sierra, Amanda; Micó, Víctor; Higuera-Gómez, Andrea; Ramos-Lopez, Omar; Daimiel, Lidia; Dávalos, Alberto; Martínez-Urbistondo, María; Moreno-Torres, Víctor; Ramirez de Molina, Ana; Vargas, Juan Antonio; Martinez, J. Alfredo (Antioxidants, 2023)
      Viral infections activate the innate immune response and the secretion of inflammatory cytokines. They also alter oxidative stress markers, which potentially can have an involvement in the pathogenesis of the disease. The ...

    • Bulevirtide in the Treatment of Hepatitis Delta: Drug Discovery, Clinical Development and Place in Therapy 

      Soriano, Vicente; Moreno-Torres, Víctor; Treviño, Ana; Corral, Octavio Jorge; de Mendoza, Carmen (Drug Design, Development and Therapy, 2023)
      It has been ten years since the identification of NTCP as the cell surface receptor for HBV and HDV entry into hepatocytes. The search for molecules interfering with the binding of NTCP and HBV/HDV led to design bulevirtide ...

    • Coinfection with Viral Hepatitis in HIV patients in 2023 

      Barreiro, Pablo; Moreno-Torres, Víctor; Soriano, Vicente (AIDS reviews, 2023)
      According to UNAIDS roughly 1.5 million new HIV infections occur each year worldwide. The number of persons living with HIV (PLWH) is estimated around 38 million globally, of whom 25 million live in Sub-Saharan Africa.

    • COVID-19 in hospitalized solid organ transplant recipients in a nationwide registry study 

      Moreno-Torres, Víctor; Martínez-Urbistondo, María; Calderón-Parra, Jorge; Mills, Patricia; Muñoz Serrano, Alejandro; Arias-Milla, Ana; Benítez, Laura; Aguilar-Pérez, Myriam; Múñez-Rubio, Elena; Ramos-Martínez, Antonio; Fernández-Cruz, Ana; Cuervas-Mons, Valentín; de Mendoza, Carmen (International Journal of Infectious Diseases, 2023)
      Objectives: Underlying immunodeficiency has been associated with worse clinical presentation and increased mortality in patients with COVID-19. We evaluated the mortality of solid organ transplant (SOT) recipients (SOTR) ...

    • Effect of the implementation of clinical guidelines on management of candidemia in elderly patients 

      Vicente Lopez, Natalia; Calderon-Parra, Jorge; Muñoz Serrano, Alejandro; Gutiérrez Villanueva, Andrea; de la Fuente, Sara; Moreno-Torres, Víctor; Muñez Rubio, Elena; Ramos Martínez, Antonio (Mycoses, 2023)
      Introduction: Mortality from candidemia is higher in elderly population than in younger patients, which may be related to suboptimal management. The aim of the present study is to evaluate adherence to the recommendations ...

    • Genetic signature detected in T cell receptors from patients with severe COVID-19 

      Corpas, Manuel; de Mendoza, Carmen; Moreno-Torres, Víctor; Pintos, Ilduara; Seoane, Pablo; Perkins, James R.; Ranea, Juan A.G.; Fatumo, Segun; Korcsmaros, Tamas; Martín-Villa, José Manuel; Barreiro, Pablo; Corral, Octavio Jorge (iScience, 2023)
      Characterization of host genetic factors contributing to COVID-19 severity promises advances on drug discovery to fight the disease. Most genetic analyses to date have identified genome-wide significant associations involving ...

    • Impact of the COVID-19 pandemic on hospital admissions due to viral hepatitis in Spain 

      Ramos-Rincón, José-Manuel; Pinargote-Celorio, Héctor; de Mendoza, Carmen; Ramos-Belinchón, Clara; Moreno-Torres, Víctor; Treviño, Ana; Barreiro, Pablo; Corral, Octavio Jorge; Soriano, Vicente (Journal of Clinical Virology, 2023)
      Background: Before the advent of COVID-19 vaccines, hospitalizations due to SARS-CoV-2 infection during 2020 collapsed most medical centers worldwide. Disruptions in health care for clinical conditions other than COVID-19 ...

    • Increased incidence of giant cell arteritis and associated stroke during the COVID-19 pandemic in Spain: A nation-wide population study 

      Moreno-Torres, Víctor; Soriano, Vicente; Calderon-Parra, Jorge; Martinez-Urbistondo, Maria; Treviño, Ana; de San Vicente, Zayrho; de Mendoza, Carmen; Ruiz-Irastorza, Guillermo (Autoimmunity Reviews, 2023)
      INTRODUCTION: SARS-CoV-2 infection and COVID-19 vaccines might have increased the incidence of giant-cell arteritis (GCA) and the risk of associated stroke in Spain. METHODS: Retrospective nation-wide observational ...

    • Intravenous cyclophosphamide improves functional outcomes in interstitial lung disease related to idiopathic inflammatory myopathies 

      Moreno-Torres, Víctor; Martín-Iglesias, Daniel; Vivero, Florencia; González-Echavarri, Cristina; García-Moyano, Marta; Enghelmayer, Juan-Ignacio; Malfante, Pablo; Gaser, Adrián; Ruiz-Irastorza, Guillermo (Seminars in Arthritis and Rheumatism, 2023)
      Objective: To compare the efficacy, toxicity and glucocorticoid (GC)-sparing effects of intravenous cyclophosphamide (iv CYC) with other immunosuppressive regimes as the induction treatment for Idiopathic Inflammatory ...

    • Is SARS-CoV-2 the only cause of long-COVID? 

      Pintos, Ilduara; Moreno-Torres, Víctor; Ibánez-Estéllez, Fatima; Corrales-Rodriguez, Pilar; Treviño, Ana; Corpas, Manuel; Corral, Octavio Jorge; Soriano, Vicente; de Mendoza, Carmen (AIDS Reviews, 2022)
      Around 10% of adults infected with SARS-CoV-2 that survive a first episode of COVID-19 appear to experience long-term clinical manifestations. The signs and symptoms of this post-acute COVID-19 syndrome (PACS) include ...

    • Pre-Exposure Prophylaxis for viral infections other than HIV 

      Soriano, Vicente; Treviño, Ana; de Mendoza, Carmen; Moreno-Torres, Víctor; Pintos, Ilduara; Barreiro, Pablo; Corral, Octavio Jorge (Infezioni in Medicina, 2022)
      The battle against human viral infections has histori-cally relied on two medical strategies, namely vaccines to protect from contagion and antivirals to treat infected patients. In the absence of vaccines, antivirals have ...

    • Predictors of in-hospital mortality in HIV-infected patients with COVID-19 

      Moreno-Torres, Víctor; de Mendoza, Carmen; Martínez-Urbistondo, María; Mills, Patricia; Treviño, Ana; de la Fuente, Sara; Diaz de Santiago, Alberto; Calderon-Parra, Jorge; Pintos, Ilduara; Corpas, Manuel; Soriano, Vicente (QJM: An International Journal of Medicine, 2023)
      Background Underlying immunodeficiency is associated with severe COVID-19, but the prognosis of persons with human immunodeficiency virus (HIV) (PWH) with COVID-19 is under debate. Aim: assessment of the mortality rate and ...

    • Prevalencia e impacto de los factores de riesgo cerebrovascular en pacientes con arteritis de células gigantes: un estudio observacional del registro nacional español 

      Sánchez-Chica, Enrique; Martínez-Urbistondo, María; Gutiérrez Rojas, Ángela; Castejón, Raquel; Vargas-Núñez, Juan A.; Moreno-Torres, Víctor (Medicina Clinica, 2023)
      Objetivo Evaluar la prevalencia e impacto de los factores de riesgo cerebrovasculares en los episodios cerebrovasculares (ECV) de pacientes con arteritis de células gigantes (ACG). Métodos Análisis de los pacientes ...

    • Rápida respuesta de lupus eritematoso cutáneo a anifrolumab 

      Moreno-Torres, Víctor; Cabeza Martínez, Rita; Mellor-Pita, Susana (Medicina Clinica, 2024)
      [Resumen no disponible]

    • Response to: Prognostic factors in hospitalized HIV-positive patients with COVID-19: correspondence 

      Moreno-Torres, Víctor; Soriano, Vicente (Support UsContactAdmin QJM: An International Journal of Medicine, 2023)
      [Abstract not available]

    • Safety considerations in the management of hepatitis C and HIV co-infection 

      Soriano, Vicente; Moreno-Torres, Víctor; Treviño, Ana; Barreiro, Pablo; de Jesús-Franco, Fernando; Corral, Octavio Jorge; de Mendoza, Carmen (Expert Opinion on Drug Safety, 2023)
      Introduction: Both HCV and HIV are highly prevalent infections with current estimates of 57 and 38 million people infected worldwide, respectively. Oral antivirals can be curative for HCV and rescue HIV patients from disease ...

    • Sequential oral antibiotic in uncomplicated Staphylococcus aureus bacteraemia: a propensity-matched cohort analysis 

      Diego-Yagüe, Itziar; Mora-Vargas, Alberto; Vázquez-Comendador, Jose Manuel; Santamarina-Alcantud, Beatriz; Fernández-Cruz, Ana; Múñez-Rubio, Elena; Gutiérrez-Villanueva, Andrea; Sanchez-Romero, Isabel; Moreno-Torres, Víctor; Ramos-Martínez, Antonio; Calderón-Parra, Jorge (Support UsContactAdmin Clinical Microbiology and Infection, 2023)
      Objectives: We aimed to analyse the efficacy and safety of oral sequential therapy (OST) in uncomplicated Staphylococcus aureus bacteraemia (SAB). Methods: Single-centre observational cohort at a tertiary hospital in Spain, ...

    • Síndrome de tako-tsubo en pacientes con vasculitis ANCA 

      Martínez-Urbistondo, María; García-Prieto, Sonia; Moreno-Torres, Víctor (Medicina Clinica, 2024)
      [Resumen no disponible]

    • Treatment of hepatitis delta and HIV infection 

      Soriano, Vicente; de Mendoza, Carmen; Treviño, Ana; Ramos-Rincón, José-Manuel; Moreno-Torres, Víctor; Corral, Octavio Jorge; Barreiro, Pablo (Liver International, 2023)
      Hepatitis delta virus (HDV) is a defective agent that only infects individuals with hepatitis B virus (HBV). Around 5–10% of chronic hepatitis B patients worldwide are superinfected with HDV, which means 15–25 million ...

    • Viral hepatitis in persons living with HIV in the post-COVID era 

      Soriano, Vicente; Moreno-Torres, Víctor; de Mendoza, Carmen; Corral, Octavio Jorge; Barreiro, Pablo (AIDS reviews, 2023)
      Coinfection with hepatitis viruses A to E is frequent in persons living with HIV (PLWH) and causes significant morbidity and mortality. Oro-fecal transmissible hepatitis A and E mostly produce acute self-limited episodes ...