Despite being COVID-19 the global focus of attention nowadays, other pandemics caused by RNA viruses are ongoing. This is the case for AIDS. Roughly, 38 million people are, at present, living with HIV-1 infection worldwide and more than 33 million have died since the beginning of the pandemic 40 years ago (de Cock K. Emerg Infect Dis 2021; 27: 1553-60).