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Up to date, a sterilizing cure of HIV-1 infection has been reported in only two persons living with HIV-1 who underwent allogeneic hematopoietic stem cell transplantations from donors who were homozygous for the CCR5 Δ32 gene polymorphism. They are known as the “Berlin patient” (Hutter et al. N Engl J Med 2009) and the “London patient” (Gupta et al. Nature 2019), respectively.

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