This research explores the influence of nepotism perception on hotel employees' intention to leave their jobs, focusing on ethical leadership as a moderator. The data collection process involved 383 employees from five-star hotels in Egypt. PLS-SEM as a significant analytical tool in hospitality research was used. The statistical data analysis was conducted using WarpPLS software version 7.0. Findings revealed that nepotism perception increases employees' intention to leave. Furthermore, a negative effect of ethical leadership exists on nepotism perception and employees' intention to leave. In addition, ethical leadership has been found to moderate the relationship between nepotism perception and employees' intention to leave. This study contributes to the hospitality literature and leadership theory by examining the interplay between nepotism perception and employees' intention to leave, with ethical leadership playing a moderating role. The findings offer insights that may prove valuable for hoteliers seeking to enhance their management practices and foster a positive work environment.