The opioid epidemic is a tragedy in the United States. In the 12-month period that ended in April 2021, more than 100,000 US citizens died of drug overdose, up almost 30% from the 78,000 deaths in the prior year.

Up to date, a sterilizing cure of HIV-1 infection has been reported in only two persons living with HIV-1 who underwent allogeneic hematopoietic stem cell transplantations from donors who were homozygous for the CCR5 Δ32 ...

Background: The clinical burden of influenza is increasing worldwide. Aging, immunosuppression, and underlying respiratory illness are determinants of poor clinical outcomes, including greater mortality. Bacterial infections ...

Historically, there has be a close relationship between the nursing services and spiritual care provision to patients, arising due to the evolvement of many hospitals and nursing programmes from faith-based institutions ...

First discovered in the late 1970s, hepatitis delta virus (HDV) has emerged as an important driver of decompensated liver disease and hepatocellular carcinoma (HCC) worldwide. HDV requires hepatitis B virus (HBV) for ...

There is a crisis of emotional well-being and mental health in adolescents and young people in developed countries (Piao et al. Eur Child Adolesc Psychiatry 2022; 31: 1827-45). Although the COVID-19 pandemic has unveiled ...

Background Underlying immunodeficiency is associated with severe COVID-19, but the prognosis of persons with human immunodeficiency virus (HIV) (PWH) with COVID-19 is under debate. Aim: assessment of the mortality rate and ...

Background: HTLV-1 infection is a neglected disease, despite producing neurological and lymphoproliferative severe illnesses and affect over 10 million people worldwide. Roughly 5% of HTLV-1 carriers develop Adult T-cell ...

Background: HTLV-1 infection is a neglected disease. Over 10 million people are infected worldwide, with hot spots of high endemicity across all continents. Roughly 5% of HTLV-1 carriers develop HTLV-1-associated myelopathy ...

This paper presents a new procedure for vaccine design against highly variable viruses such as Hepatitis C. The procedure uses an optimization algorithm to design vaccines that maximize the coverage of epitopes across ...