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Trends in hospitalizations and deaths in HIV-infected patients in Spain over two decades
(AIDS, 2022-02)
Background: The prognosis of HIV infection dramatically improved after the introduction of triple antiretroviral therapy 25 years ago. Herein, we report the impact of further improvements in HIV management since then, ...
Impact of scaling up SARS-CoV-2 vaccination on COVID-19 hospitalizations in Spain
(Elsevier B.V., 2021)
Background: The advent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines has been associated with a significant decline in coronavirus disease 2019 (COVID-19) hospitalizations and deaths. However, ...
Envisioning a hepatitis delta cure with new antivirals
(Future Medicine Ltd., 2021)
Envisioning a hepatitis delta cure with new antivirals
Main differences between the first and second waves of COVID-19 in Madrid, Spain
(International journal of infectious diseases, 2021)
Background: The emergence and rapid global spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) represents a major challenge to health services, and has disrupted social and economic activities worldwide. ...
Third wave of COVID-19 in Madrid, Spain
(Innoeduca-international journal of infectious diseases, 2021)
A third wave of COVID-19 occurred after Christmas 2020 in Madrid, one of the European pandemic epicenters. We noticed 6 major differential features to previous waves. First, household contacts were a large proportion of ...
Ultra-long-acting antivirals as chemical vaccines to prevent viral diseases
(Future Microbiology, 2022-07)
For two centuries, vaccines have been successful in the fight against viruses, triggering immune protection. Indeed, the elimination of smallpox, the only infectious disease eradicated to date, was made possible through ...
Oral antivirals for the prevention and treatment of SARS-CoV-2 infection
(AIDS Reviews, 2022)
Vaccines and antivirals are the classical weapons deployed to contain, prevent, and treat life-threatening
viral illnesses. Specifically, for SARS-CoV-2 infection, vaccines protect against severe COVID-19 disease
manifestations ...
Pre-Exposure Prophylaxis for viral infections other than HIV
(Infezioni in Medicina, 2022)
The battle against human viral infections has histori-cally relied on two medical strategies, namely vaccines to protect from contagion and antivirals to treat infected patients. In the absence of vaccines, antivirals have ...
News from CROI 2022 – caveats using antiretrovirals as HIV prophylaxis
(AIDS Reviews, 2022)
The annual conference on retroviruses and opportunistic infections was held in Denver, CO, last February. Most sessions were attended by virtual attenders, due to restrictions forced by the COVID-19 surge caused by the ...
Hepatitis C hospitalizations in Spain and impact of new curative antiviral therapies
(Journal of Viral Hepatitis, 2022)
Chronic hepatitis C virus (HCV) infection is major cause of decompensated cirrhosis and liver cancer. The advent of curative new antiviral therapies since year 2015 has dramatically improved the prognosis of HCV patients. ...