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Listar RESULTADOS DE INVESTIGACIÓN por autor "Yañez-Diaz, Sonsoles"
Mostrando ítems 1-4 de 4
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A Comparison Between Recombinant Listeria GAPDH Proteins and GAPDH Encoding mRNA Conjugated to Lipids as Cross-Reactive Vaccines for Listeria, Mycobacterium, and Streptococcus
Teran-Navarro, Héctor; Salcines-Cuevas, David; Calderón-González, Ricardo; Tobes, Raquel; Calvo-Montes, Jorge; Pérez-Del Molino Bernal, Inmaculada Concepción; Yañez-Diaz, Sonsoles; Fresno, Manuel; Álvarez-Domínguez, Carmen (Frontiers in immunology, 2021)Cross-reactive vaccines recognize common molecular patterns in pathogens and are able to confer broad spectrum protection against different infections. Antigens common to pathogenic bacteria that induce broad immune ... -
Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase
Álvarez-Domínguez, Carmen ; Salcines-Cuevas, David; Teran-Navarro, Héctor; Calderón-González, Ricardo; Tobes, Raquel; García, Isabel; Grijalvo, Santiago; Paradela, Alberto; Seoane, Asunción; Sangari, Felix J.; Fresno, Manuel; Calvo-Montes, Jorge; Pérez Del Molino Bernal, I. Concepción; Yañez-Diaz, Sonsoles (Frontiers in Cellular and Infection Microbiology, 10/2020)The glycolytic enzyme and bacterial virulence factor of Listeria monocytogenes, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH, Lmo2459), ADP-ribosylated the small GTPase, Rab5a, and blocked phagosome maturation. This ... -
Glyceraldehyde-3-phosphate dehydrogenase common peptides of listeria monocytogenes, mycobacterium marinum and streptococcus pneumoniae as universal vaccines
Salcines-Cuevas, David; Teran-Navarro, Héctor; Calderón-González, Ricardo; Torres-Rodriguez, Paula; Tobes, Raquel; Fresno, Manuel; Calvo-Montes, Jorge; Pérez Del Molino-Bernal, Concepción; Yañez-Diaz, Sonsoles; Álvarez-Domínguez, Carmen (Vaccines, 2021)Universal vaccines can be prepared with antigens common to different pathogens. In this regard, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a common virulence factor among pathogenic bacteria of the genera ... -
Gold Glyconanoparticles Combined with 91–99 Peptide of the Bacterial Toxin, Listeriolysin O, Are Efficient Immunotherapies in Experimental Bladder Tumors
Terán-Navarro, Hector; Zeoli, Andrea; Salines-Cuevas, David; Marradi, Marco; Montoya, Noemí ; Gonzalez-Lopez, Elena; Ocejo-Vinyals, J. Gonzalo; Dominguez-Esteban, Mario; Gutierrez-Baños, Jose Luis; Campos-Juanatey, Felix; Yañez-Diaz, Sonsoles; Garcia-Castaño, Almudena; Rivera, Fernando; Duran, Ignacio; Álvarez-Domínguez, Carmen (Cancers, 2022)This study presents proof of concept assays to validate gold nanoparticles loaded with the bacterial peptide 91–99 of the listeriolysin O toxin (GNP-LLO91–99 nanovaccines) as immunotherapy for bladder tumors. GNP-LLO91–99 ...