• Genetic signature detected in T cell receptors from patients with severe COVID-19 

      Corpas, Manuel; de Mendoza, Carmen; Moreno-Torres, Víctor; Pintos, Ilduara; Seoane, Pablo; Perkins, James R.; Ranea, Juan A.G.; Fatumo, Segun; Korcsmaros, Tamas; Martín-Villa, José Manuel; Barreiro, Pablo; Corral, Octavio Jorge (iScience, 2023)
      Characterization of host genetic factors contributing to COVID-19 severity promises advances on drug discovery to fight the disease. Most genetic analyses to date have identified genome-wide significant associations involving ...
    • Transferability of genetic risk scores in African populations 

      Kamiza, Abram B; Toure, Sounkou M.; Vujkovic, Marijana; Machipisa, Tafadzwa; Soremekun, Opeyemi S.; Kintu, Christopher; Corpas, Manuel ; Pirie, Fraser; Young, Elizabeth; Gill, Dipender; Sandhu, Manjinder S.; Kaleebu, Pontiano; Nyirenda, Moffat; Motala, Ayesha A.; Chikowore, Tinashe; Fatumo, Segun (Nature Medicine, 2022)
      A new study reveals that polygenic scores for lipid traits derived from data of African American individuals have high predictive value in a South African Zulu cohort but are poor predictors in a cohort from Uganda, further ...