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Listar por autor "Meléndez-Hevia, Enrique"
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Glycine can prevent and fight virus invasiveness by reinforcing the extracellular matrix
Meléndez-Hevia, Enrique; Paz-Lugo, Patricia de ; Sánchez, Guillermo (Journal of Functional Foods, 01/2021)The extracellular matrix, mainly composed of collagen, is a mechanical barrier against infective agents, including viruses. High glycine availability is needed for a healthy collagen turnover. Glycine produced by human ... -
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis
Paz-Lugo, Patricia de ; Lupiáñez, José Antonio; Meléndez-Hevia, Enrique (Amino Acids, 10/2018)Collagen synthesis is severely diminished in osteoarthritis; thus, enhancing it may help the regeneration of cartilage. This requires large amounts of glycine, proline and lysine. Previous works of our group have shown ...